Is ethylene oxide used to sterilize?

Ethylene oxide sterilization advantages and disadvantages

Today, ethylene oxide sterilization (ETO) has evolved to a high level of performance and efficiency. It is now a proven technology for thermosensitive products, which cannot be sterilized by other traditional sterilization methods such as steam or heat.

This chemical sterilization process based on the diffusion of a gas, ethylene oxide or ETO, is capable of sterilizing and destroying micro-organisms. It is a low-temperature sterilization method since it works with temperatures not exceeding 60º C.

It is important to know that this gas is explosive and toxic. Therefore, it must always be used with great safety, working with sterilization equipment that ensures the safety of the personnel, the work environment and the environment.

This sterilization process is used in the medical and pharmaceutical sector. The elements that are usually sterilized by ethylene oxide are all the elements or materials that cannot be sterilized with the traditional process.

How is ethylene oxide used for sterilization?

Ethylene Oxide Sterilization

Based on a gas diffusion process, ethylene oxide (EO or ETO) is capable of sterilizing and rendering products free of viable microorganisms. Sterilization occurs when a molecule of EO gas reacts with microbial DNA and destroys it.

What type of sterilization is ethylene oxide?

Ethylene Oxide sterilization method. … This chemical sterilization process based on the diffusion of a gas, ethylene oxide or ETO, is capable of sterilizing and destroying micro-organisms. It is a low temperature sterilization method since it works with temperatures that do not exceed 60º C.

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What is used for sterilization?

Physical methods are carried out through the use of moist heat, dry heat or radiation, destroying all forms of microbial life, including spores, the most commonly used method is pressurized steam. Pressurized steam-moist heat. Hot air-dry heat. Ionizing radiation.

Ethylene oxide for sterilization

Based on a gas diffusion process, ethylene oxide (EO or ETO) is capable of sterilizing and rendering products free of viable microorganisms. Sterilization occurs when a molecule of EO gas reacts with microbial DNA and destroys it. The process requires simultaneous control of four variable but interdependent parameters: gas concentration, temperature, relative humidity and exposure time. The effectiveness of EO sterilization depends on its ability to diffuse freely in a product and container. All products should be placed in porous packaging that allows the gas to penetrate the sterile barrier system and reach all surfaces of the device or product.

EO is considered the most widely applicable sterilization method available for medical products and devices due to its effectiveness at lower temperatures and its general compatibility with a variety of materials, resins and product types, including the following:

What kind of materials can be sterilized in the autoclave?

Items made of stainless steel, glass and plastics such as PP (polypropylene), PMP (polymethylpentene) or PTFE/PFA (Teflon) can be autoclaved.

How is ethylene oxide used?

Ethylene oxide is a flammable gas used in the manufacture of ethylene glycol, a substance used in the production of antifreeze and polyester. This chemical is also used in very small quantities in hospitals to sterilize medical equipment and materials.

How is ethylene applied?

Chemical: Ethylene is the raw material for several industrial syntheses. It is used as an intermediate in the chemical industry and for the production of plastics. Food and Beverage: An ethylene/nitrogen mixture supplied in cylinders is used to control the ripening of fruits, especially bananas.

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Ethylene oxide sterilization time

Ethylene oxide (EtO) sterilization is mainly used to sterilize medical and pharmaceutical products that cannot withstand conventional high-temperature sterilization, such as devices incorporating electronic components, packaging or plastic containers.

EtO gas is filtered into the packages as well as the products themselves to kill microorganisms remaining after the production or packaging process. This gas, when mixed with air in a ratio of at least 3 % EtO gas, forms an explosive mixture. The boiling point of pure EtO gas is 10.73 °C at atmospheric pressure. It is normally mixed with nitrogen or CO2. This explosive condition requires the use of intrinsically safe materials (ATEX) zones, both for the safety of people and for the safety of the process itself.

When this toxic gas is removed from the room, it must be treated by thermal burners, scrubbing or oxidation for environmental protection or transported to other facilities for treatment.

How is the sterilization process carried out?

Sterilization is the process capable of eliminating all forms of microbial life including spores by physical (dry heat, moist heat), chemical (liquid or gaseous), physical-chemical (such as those that combine chemical gases and vapors at low temperature) or plasma (hydrogen peroxide) methods, In order for this process to be effective, it must be carried out by a …

What is autoclave sterilization like?

There are two ways to kill using heat, by coagulation or by oxidation. Autoclave sterilization uses coagulation in the form of highly pressurized steam to denature the proteins within the microorganisms.

What type of material can be sterilized by moist heat?

Rubber gloves 15 minutes. Probes (woven base) 15 minutes. Probes (latex) 15 minutes. Glass Bottles, Glassware in General 20 minutes.

Ethylene oxide sterilization of mouthpieces

Today, ethylene oxide sterilization (ETO) has evolved to a high level of performance and efficiency. It is now a proven technology for thermosensitive products, which cannot be sterilized by other traditional sterilization methods such as steam or heat.

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This chemical sterilization process based on the diffusion of a gas, ethylene oxide or ETO, is capable of sterilizing and destroying micro-organisms. It is a low-temperature sterilization method since it works with temperatures not exceeding 60º C.

It is important to know that this gas is explosive and toxic. Therefore, it must always be used with great safety, working with sterilization equipment that ensures the safety of the personnel, the work environment and the environment.

This sterilization process is used in the medical and pharmaceutical sector. The elements that are usually sterilized by ethylene oxide are all the elements or materials that cannot be sterilized with the traditional process.